CSP01: Cyclosporin A [CAS # 59865-13-3]

CSP02: Cyclosporin B [CAS # 63775-95-1]

CSP03: Cyclosporin C [CAS # 59787-61-0]

CSP04: Cyclosporin D [CAS # 63775-96-2]

CSP05: Cyclosporin H [CAS # 83602-39-5]

Cyclosporine (also known as Cyclosporin A or Ciclosporin A) is a nonpolar cyclic oligopeptide with immunosuppressant activity, produced by Tolypocladium inflatum.

Physico-Chemical Properties:
White crystals, mp: 148-152 DC, [a]D20: - 244 (c = 0.6 in chloroform); Soluble in methanol, ethanol, acetone, ethyl acetate, chloroform, diethyl ether; slightly soluble in hexane, petroleum ether; insoluble in water.

References:

A. Rüegger et al., Helv. Chim. Acta 59, 1075 (1976);
M. Dreyfuss et al., Eur. J. Appl. Microbiol. 3, 125 (1976);
E. Härri et al., US 4117118 (1978 to Sandoz).
R. Wenger, Transplant. Proc. 15(4), Suppl. 1, 2230 (1983)
P. E. Wallemacq et al., J. Chromatog. 413, 131 (1987)