Catalog #: VCM00

Product Name: Vancomycin Hydrochloride

CAS Registry Number: 1404-93-9

Vancomycin Hydrochloride is a glycopeptide antibiotic produced by Streptomyces orientalis, it inhibits bacterial cell wall synthesis by binding to peptidoglycan.

Physico-Chemical Properties:

White or off white powder; UV max (water) at 282 nm (E1%1cm 40); Soluble in water (>100 mg/ml); moderately soluble in dilute methanol & ethanol; insoluble in acetone, ether, chloroform, ethyl acetate.

References:

Isolation, Purification and Structure Determination:

M. McCormick et al., Antibiot. Ann. 1955-56, 606;
M. McCormick et al., US Patent # 3067099 (1962 to Lilly).

Synthesis: N/A

HPLC Analysis:

J. Diana, et al., J. Chromatogr. A. 2003 May 9;996(1-2):115-31
D. Backes, et al., J. Pharm. Biomed. Anal. 1998 Apr;16(8):1281-7.

VCM01: Vancomycin EP Impurity A

Synonym: N-Desmethyl Vancomycin B

VCM02: Vancomycin EP Impurity B

Synonym: [ß Asp3] Vancomycin B ; Vancomycin B Diacid

VCM03: Vancomycin EP Impurity C

Synonym: Agluco Vancomycin B ; Vancomycin B Aglycone

VCM04: Vancomycin EP Impurity D

Synonym: Desvancosaminyl Vancomycin B

VCM05: Vancomycin Didechloro Impurity

Synonym: Didechloro Vancomycin B