PSM02A: Pristinamycin IIA

PSM02A: Pristinamycin IIA

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Pristinamycin IIA ;

Antibiotic PA-114A ;

Antibiotic PA-114A1;

Factor M ;

Mikamycin A ;

NSC-244426 ;

NSC-87432 ;

Ostreogrycin A ;

PA-114A ;

RP-12536 ;

Staphylomycin M1 ;

Streptogramin A ;

Synergistin A1 ;

Vernamycin A ;

Virginiamycin M1 ;

8,9,14,15,24,25-Hexahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)(3R,4R,5E,10E,12E,14S)-3H-21,18-nitrolo-1H,22H-pyrrolo[2,1-c][1,8,4,19]-dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone ;

CAS # 21411-53-0 ; 270076-60-3 (Mixture of Pristinamycin IA & IIA) ;

C28H35N3O7 ;

MW: 525.59 ;

Impurity and intermediate of dalfopristin (ingredient for Synercid) ;

Pristinamycin is a streptogramin group antibiotic used primarily for the treatment of staphylococcal infections, and to a lesser extent streptococcal infections. It is marketed in Europe by Sanofi-Aventis under the trade name "Pyostacine" which is a mixture of two components, ie, Pristinamycin IA and Pristinamycin IIA (30 : 70) with synergistic antibacterial action.

Pristinamycin IA may contain a minor impurity "Pristinamycin IB" (= "N-Desmethyl Pristinamycin IA").

Pristinamycin IIA may contain a minor impurity "Pristinamycin IIB" (= "Dihydro Pristinamycin IIA").